Constante tempo membrana τ
- Created by
- Renato Passos, Eng. de Software
- Reviewed by
- Renato Passos, Eng. de Software
Last updated: Apr 18, 2026
About this calculator
The membrane time constant (τ) calculator determines how long a cell membrane takes to reach ~63% of its electrical response to a stimulus. The formula τ = R_m × C_m combines membrane resistance (R_m) and membrane capacitance (C_m). This is essential for studying neuronal action potentials, cardiac electrophysiology, and cellular signal dynamics.
This constant governs how quickly a membrane charges or discharges. In biomedical applications, τ guides electrical stimulation protocols for nerve therapies and neural interfaces. In biomedical engineering, it informs electrode and sensor design. R_m typically ranges from 10^7 to 10^8 ohms, while C_m varies between 1, 20 µF/cm² depending on cell type.
For accurate results, measure R_m and C_m experimentally. Consider biological variables like ion channel activity or temperature fluctuations, which can alter real-world parameters. τ also serves as a diagnostic tool in toxin/drug research to detect membrane integrity changes.
τ is dynamic in excitable cells like neurons. Variations in τ may signal ionic channel dysfunction or pathological conditions. Always contextualize results within the specific biological or experimental framework to ensure meaningful interpretation.
Frequently asked questions
What does the membrane time constant measure?
It quantifies how fast a cell membrane charges in response to electrical stimuli, critical for understanding nerve signal propagation.
What units are used for R_m and C_m?
R_m is in ohms (Ω), C_m in farads (F), typically measured in microfarads (µF).
How does temperature affect τ?
Higher temperatures decrease both R_m and C_m, reducing τ and accelerating membrane response.
Why is τ used in drug research?
It helps detect chemical effects on ion channels or membrane integrity through τ changes.
Is the calculation applicable to all cell types?
No, as R_m and C_m vary by cell structure and function, requiring type-specific calibration.