Potencial Nernst K⁺

E = (RT/zF)·ln([K]out/[K]in).
Created by
Renato Passos, Eng. de Software
Reviewed by
Renato Passos, Eng. de Software

Last updated: Apr 18, 2026

E_K
-89,01 mV

About this calculator

The Potassium Nernst Potential calculator computes the electric potential generated by potassium ion (K⁺) concentration differences between a cell's interior and exterior. It uses the Nernst equation: E = (RT/zF)·ln([K]out/[K]in), where R is the gas constant, T is temperature, z is ion valence, F is Faraday's constant, and [K]out/[K]in are extracellular/intracellular concentrations. Results are in volts or millivolts, depending on temperature and concentration units.

This formula is critical in biophysics for understanding ionic equilibrium in cell membranes, especially in neurons and muscles. For example, it calculates resting membrane potentials in nerve cells, where K⁺ tends to exit the cell, creating an internal negative potential. The calculation accounts for temperature (in Kelvin) and concentration ratios, which vary by tissue and physiological state.

Note that the calculator assumes ideal conditions, such as membrane selectivity for K⁺ alone and negligible contributions from other ions. In real scenarios, factors like ambient temperature, concentration fluctuations, and presence of other ions (Na⁺ or Cl⁻) may affect results. Users should cross-check input data with experimental values or reliable references for higher accuracy.

Frequently asked questions

Why is the Nernst potential important in nerve cells?

The Nernst potential sets the electrochemical balance from K⁺ efflux, stabilizing the resting membrane potential. This is crucial for nerve impulse transmission and cellular responses to external stimuli.

How to convert temperature to Kelvin in the formula?

Add 273.15 to the Celsius value. For example, 25°C becomes 298.15 K.

What if concentrations are in different units?

The calculator requires [K]out and [K]in to be in the same unit (e.g., mmol/L). Convert values to match before entering.

Does this formula work for other ions besides K⁺?

Yes, but each ion has a specific valence (z). Adjust z for Na⁺ or Cl⁻ accordingly.

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