Log P (coef partição)

log P = log(C_oct/C_aq).
Created by
Renato Passos, Eng. de Software
Reviewed by
Renato Passos, Eng. de Software

Last updated: Apr 18, 2026

log P
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Formula

log P

About this calculator

The Log P (partition coefficient) calculator is a useful tool for chemists and researchers working with chemical substances. It calculates the logarithm of the partition coefficient, which is a measure of a substance's ability to distribute between two immiscible phases, such as octanol and water.

The log P is calculated as the logarithm of the ratio of the substance's concentration in octanol (C_oct) to its concentration in water (C_aq). This provides a measure of the substance's lipophilicity, or its ability to dissolve in organic solvents.

The Log P calculator is useful in a variety of applications, including predicting the absorption and distribution of chemical substances in the human body, as well as evaluating the toxicity and environmental potential of chemical substances.

It is important to be cautious when using the Log P calculator, as the accuracy of the result depends on the accuracy of the input concentrations. Additionally, it is essential to understand the limitations of the calculator and consider other factors that may affect the distribution of chemical substances.

Frequently asked questions

What is log P?

Log P is the logarithm of the partition coefficient, which is a measure of a substance's ability to distribute between two immiscible phases, such as octanol and water.

How is log P calculated?

Log P is calculated as the logarithm of the ratio of the substance's concentration in octanol (C_oct) to its concentration in water (C_aq).

What is the importance of log P?

Log P is important for predicting the absorption and distribution of chemical substances in the human body and evaluating the toxicity and environmental potential of chemical substances.

What are the limitations of the Log P calculator?

The accuracy of the result depends on the accuracy of the input concentrations and it is essential to consider other factors that may affect the distribution of chemical substances.

How to use the Log P calculator?

Just enter the concentrations of the substance in octanol and water and click the calculate button to get the log P.

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