Prob. fixação por deriva

P = 1/(2N) para alelo neutro novo.
Created by
Renato Passos, Eng. de Software
Reviewed by
Renato Passos, Eng. de Software

Last updated: Apr 18, 2026

P fixação
0,001000

About this calculator

The "Fixation probability by drift" calculator estimates the chance of a new neutral allele becoming fixed in a population through genetic drift. The formula used is P = 1/(2N), where N is the effective population size. This applies to diploid populations, where each individual has two alleles per locus, and assumes the allele has no selective advantage or disadvantage.

To use the calculator, input the population size (N). The result shows the likelihood the allele will become the only copy in the population over time. In small populations, genetic drift has stronger effects, increasing fixation chances. In large populations, the probability approaches zero, reflecting greater genetic stability.

This calculation is valuable in population genetics studies, such as conservation biology or theoretical simulations. However, the model is simplified. Factors like natural selection, gene flow, and population size fluctuations can affect real-world outcomes not accounted for in this formula.

Note: The 1/(2N) formula applies only to new neutral alleles. If the allele already exists in multiple copies or affects organismal survival, more complex models are required. The calculator provides theoretical foundations but does not replace detailed genetic analysis in applied contexts.

Frequently asked questions

What is a neutral allele?

A neutral allele does not affect an organism's survival or reproduction. Its frequency changes in the population purely by chance, not through natural selection.

Why is the formula 1/(2N) instead of 1/N?

In diploid populations, each individual has two alleles per locus. The 2N represents the total number of alleles in the population, accounting for all chromosomes.

Does this calculator work for polyploid populations?

No. The 1/(2N) formula is specific to diploid organisms. Polyploid populations would require adjusted formulas for accurate calculations.

Can I use this calculator for beneficial alleles?

No. The formula assumes neutrality. Beneficial or deleterious alleles require models that incorporate selection, such as the Fisher-Wright equation.

What does allele fixation mean?

Fixation occurs when an allele reaches 100% frequency in the population, becoming the only allele present for that genetic locus.

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