Coeficiente endogamia F

F = 1 - (H_o / H_e).
Created by
Renato Passos, Eng. de Software
Reviewed by
Renato Passos, Eng. de Software

Last updated: Apr 18, 2026

F
0,400

Formula

1 - H_o/H_e

About this calculator

The inbreeding coefficient (F) measures inbreeding levels in a population by comparing observed heterozygosity (H_o) to expected heterozygosity (H_e) under Hardy-Weinberg equilibrium. When F = 0, the population is in equilibrium; positive values indicate inbreeding, while negative values suggest increased heterozygosity due to factors like gene flow. The formula F = 1 - (H_o/H_e) is widely used in population genetics to assess genetic diversity reduction.

To calculate F, input observed (H_o) and expected (H_e) heterozygosity values. The calculator divides H_o by H_e and subtracts from 1. Values close to 1 indicate extreme inbreeding, while negative F suggests equilibrium deviations from other factors. Results help identify selective pressures, gene flow, or population structure.

This calculation is critical in conservation biology, breeding programs, and evolutionary history studies. For example, in endangered species, high F warns of inbreeding risks. In livestock breeding, it helps avoid mating between close relatives. For domesticated species, it reveals domestication's impact on genetic variability.

Interpret results cautiously: the formula assumes Hardy-Weinberg equilibrium and representative samples. Sampling errors, artificial selection, or mutations can distort H_o and H_e. Atypical values should be reexamined with complementary methods like population structure analysis.

Frequently asked questions

What does a positive F coefficient indicate?

A positive F indicates inbreeding, meaning increased mating between close relatives, reducing population heterozygosity.

How are H_o and H_e calculated?

H_o is derived from population samples; H_e is calculated using theoretical allele frequencies under Hardy-Weinberg equilibrium.

Can this be used for any population?

The formula applies to populations in Hardy-Weinberg equilibrium. For structured populations, additional analysis methods are recommended.

Why is my result negative?

Negative F suggests higher heterozygosity than expected, possibly due to gene flow or directional selection.

How does inbreeding affect genetic diversity?

Inbreeding increases homozygosity, reducing genetic diversity and increasing risks of expressing harmful recessive alleles.

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