Energia hidrólise ATP

ΔG°' = -30.5 kJ/mol (celular ~ -50 kJ/mol).
Created by
Renato Passos, Eng. de Software
Reviewed by
Renato Passos, Eng. de Software

Last updated: Apr 18, 2026

ΔG (kJ/mol)
-36,4

Formula

ΔG = ΔG° + RT·ln([ATP]/[ADP])

About this calculator

The ATP hydrolysis energy calculator computes the free energy change (ΔG) for the reaction ATP → ADP + Pi using ΔG = ΔG°' + RT·ln([ATP]/[ADP]). The standard ΔG°' is -30.5 kJ/mol, but in cellular conditions, it's ~-50 kJ/mol due to ATP/ADP concentration ratios. This tool is critical for understanding ATP's role as the 'energy currency' in cells.

The formula accounts for ATP/ADP concentration ratios, which vary across cell types and metabolic states. The calculator lets users input [ATP], [ADP], and [Pi] to simulate biological scenarios. It's widely used in biochemistry to study cellular respiration, fermentation, and protein synthesis, where ATP acts as an energy driver.

For accurate results, input concentrations in mol/L, temperature in Kelvin, and maintain constant pressure. Extreme values may indicate cellular imbalances. While not a substitute for advanced software, this calculator offers quick estimates for introductory studies or theoretical analysis.

ATP is the primary energy carrier in cells. Its hydrolysis releases -30.5 kJ/mol under standard conditions, but in living cells, this can reach -50 kJ/mol due to low ADP levels. The calculator helps analyze how factors like temperature, pH, and enzymes (e.g., ATPase) affect energy efficiency in biological processes.

Frequently asked questions

What is the difference between standard ΔG and cellular ΔG?

Standard ΔG (-30.5 kJ/mol) is measured under ideal lab conditions. Cellular ΔG (~-50 kJ/mol) reflects actual ATP/ADP concentrations in metabolically active cells.

Why does the formula use the [ATP]/[ADP] ratio?

The ratio determines the reaction's direction. In cells, low ADP levels keep ΔG more negative, favoring ATP hydrolysis to release energy.

Does temperature affect the calculator's results?

Yes, temperature affects the RT·ln([ATP]/[ADP]) term. Higher Kelvin values increase thermal energy available to the system, altering the calculated ΔG.

What studies benefit most from this calculator?

It's ideal for metabolic research, cellular biochemistry, and analyzing enzyme-driven reactions that depend on ATP as an energy source.

Can I use non-experimental concentration values?

Yes, but theoretical results may not reflect real conditions. Use it for educational simulations or hypotheses, always validating with experimental data.

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